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Written for drug developers rather than computer scientists, this monograph adopts a systematic approach to mining scientifi c data sources, covering all key steps in rational drug discovery, from compound screening to lead compound selection and personalized medicine....
Editeur :
Wiley-VCH
Parution :
2013-09-25
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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Most of the antibiotics now in use have been discovered more or less by chance, and their mechanisms of action have only been elucidated after their discovery. To meet the medical need for next-generation antibiotics, a more rational approach to antibiotic development...
Editeur :
Wiley-VCH
Parution :
2013-09-04
PDF, ePub
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At the moment, there is no dedicated book to summarize the roles, the significance, and potential therapeutic targeting of transcriptional factors from the perspective of signaling cascade, and thus, directly impacting the functionality of transcriptional factors in...
Editeur :
Humana
Parution :
2013-08-23
Collection :
Cancer Drug Discovery and Development
ePub
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This comprehensive, unified text on the principles and practice of clinical trials presents a detailed account of how to conduct the trials. It describes the design, analysis, and interpretation of clinical trials in a non-technical manner and provides a general...
Editeur :
Wiley
Parution :
2013-07-17
PDF, ePub
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Textbook of Pharmacoepidemiology, Second Edition, provides an introduction to pharmacoepidemiology and the data sources, methods and applications used in clinical research, the pharmaceutical industryand regulatory agencies. Drawing upon the fifth edition of the...
Editeur :
Wiley-Blackwell
Parution :
2013-07-08
PDF, ePub
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Most medicines have never been adequately tested for safety and efficacy in pediatric populations and preterm, infants and children are particularly vulnerable to adverse drug reactions.Pediatric Drug Development: Concepts and Applications, Second Edition, addresses the...
Editeur :
Wiley-Blackwell
Parution :
2013-05-20
PDF, ePub
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The latest edition of this highly acclaimed textbook, provides a comprehensive and up-to-date overview of the science and medical applications of biopharmaceutical products. Biopharmaceuticals refers to pharmaceutical substances derived from biological sources, and...
Editeur :
Wiley-Blackwell
Parution :
2013-04-29
ePub
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This book provides the reader with a contemporary and comprehensive overview about the molecular, cellular and system-wide principles of circadian clock regulation. Emphasis is placed on the importance of circadian clocks for the timing of therapeutic interventions.
Editeur :
Springer
Parution :
2013-04-18
Collection :
Handbook of Experimental Pharmacology
ePub
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The Textbook of Pharmaceutical Medicine is the standard reference for everyone working and learning in pharmaceutical medicine. It is a comprehensive resource covering the processes and practices by which medicines are developed, tested and approved, and the recognised...
Editeur :
BMJ Books
Parution :
2013-03-29
PDF, ePub
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The misfolding and aggregation of specific proteins is an early and obligatory event in many of the age-related neurodegenerative diseases of humans.The initial cause of this pathogenic cascade and the means whereby disease spreads through the nervous system, remain...
Editeur :
Springer
Parution :
2013-03-27
Collection :
Research and Perspectives in Alzheimer's Disease
ePub
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Quantitative Research Methods for Health Professionals: A Practical Interactive Course is a superb introduction to epidemiology, biostatistics, and research methodology for the whole health care community. Drawing examples from a wide range of health research, this...
Editeur :
Wiley-Interscience
Parution :
2013-03-18
PDF
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"The goal is to provide a comprehensive reference book for the preclinicaldiscovery and development scientist whose responsibilities span target identification, lead candidate selection, pharmacokinetics, pharmacology, and toxicology, and for regulatory scientists whose...
Editeur :
Wiley-Interscience
Parution :
2013-03-07
PDF, ePub
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Nonclinical Safety AssessmentNonclinical Safety Assessment A Guide to International Pharmaceutical Regulations Bringing a new drug to market is a costly time-consuming process. Increased regional and international regulation over the last twenty years, while...
Editeur :
Wiley
Parution :
2013-03-05
PDF, ePub
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Important safety aspects of compatibility for therapeutic products and their manufacturing systems, delivery devices, and containers Compatibility of Pharmaceutical Products and Contact Materials helps pharmaceutical, toxicology, analytical, and regulatory affairs...
Editeur :
Wiley-Interscience
Parution :
2013-02-26
PDF, ePub
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Die pharmazeutische Mikrobiologie hat sich in den letzten Jahrzehnten von einer hochspezialisierten Wissenschaft zu einer Querschnittdisziplin entwickelt, die fur Pharmazeuten, Mikrobiologen, aber auch Mediziner und Qualitatssicherungsbeauftragte von fundamentaler...
Editeur :
Wiley-VCH
Parution :
2013-02-11
PDF, ePub
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This book will be the first that focuses on solely on model organisms for lymphoma. It's editors are internationally recognized in the field.
Editeur :
Humana
Parution :
2013-02-01
Collection :
Cancer Drug Discovery and Development
ePub
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The contents of this book will be organized into three sections.The first section defines the scope, impact and behaviour of cancer regimen-related toxicities and frames the issue of balancing treatment success and physiological cost. In the second segment of the book,...
Editeur :
Springer
Parution :
2013-01-28
ePub
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The need for novel antibiotics is greater now than perhaps any time since the pre-antibiotic era. Indeed, the recent collapse of many pharmaceutical antibacterial groups, combined with the emergence of hypervirulent and pan-antibiotic-resistant bacteria has severely...
Editeur :
Wiley-Blackwell
Parution :
2013-01-14
Collection :
Life Science Research Fundamentals
ePub
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Metastatic disease is the most lethal aspect of human malignancies, making the understanding and continued research of the process of metastasis a crucial step in treating cancer. The proposed book, entitled “Experimental and Clinical Metastasis: A Comprehensive Review”...
Editeur :
Springer
Parution :
2013-01-04
ePub
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Treating protein-protein interactions as a novel and highly promising class of drug targets, this volume introduces the underlying strategies step by step, from the biology of PPIs to biophysical and computational methods for their investigation. The main part of the...
Editeur :
Wiley-VCH
Parution :
2013-01-02
Collection :
Methods & Principles in Medicinal Chemistry
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