Télécharger le livre :  Gene and Cellular Immunotherapy for Cancer
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Clinical and preclinical exploration of gene and cellular immunotherapy have seen rapid growth and interest with the development and approval of five Chimeric Antigen Receptor T-cell (CAR-T) products for lymphoma and myeloma and one Bispecific T-Cell Engager (BiTE) for...

Editeur : Humana
Parution : 2022-01-01
Collection : Cancer Drug Discovery and Development
PDF, ePub

157,74
Télécharger le livre :  Molecular Targeted Radiosensitizers
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Molecular Targeted Radiosensitizers: Opportunities and Challenges provides the reader with a comprehensive review of key pre-clinical research components required to identify effective radiosensitizing drugs. The book features discussions on the mechanisms and markers...

Editeur : Humana
Parution : 2020-08-10
Collection : Cancer Drug Discovery and Development
PDF, ePub

147,69
Télécharger le livre :  The Unfolded Protein Response in Cancer
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This volume presents state-of-the-art information on each of the arms of the unfolded protein response (UPR), how their activation/repression are regulated, integrated, and coordinated, how UPR components affect cancer cell biology and responsiveness to therapeutic...

Editeur : Humana
Parution : 2019-03-01
Collection : Cancer Drug Discovery and Development
PDF, ePub

94,94
Télécharger le livre :  Estrogen Receptor and Breast Cancer
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The discovery of ER by Dr. Elwood Jensen exactly 60 years ago has not only led to the birth of a whole new vital nuclear receptor research field but also made a rapid, direct and lasting impact on the treatment and prevention of breast cancer. Since that landmark...

Editeur : Humana
Parution : 2018-10-16
Collection : Cancer Drug Discovery and Development
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168,79
Télécharger le livre :  Innovations for Next-Generation Antibody-Drug Conjugates
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Antibody-drug conjugates (ADCs) stand at the verge of a transformation.  Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges.  This volume...

Editeur : Humana
Parution : 2018-05-29
Collection : Cancer Drug Discovery and Development
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147,69
Télécharger le livre :  Targeting the DNA Damage Response for Anti-Cancer Therapy
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Over the past decade a complex role for DNA damage response (DDR) in tumorigenesis has emerged. A proficient DDR has been shown to be a primary cause for cellular resistance to the very many DNA damaging drugs, and IR, that are widely used as standard-of-care...

Editeur : Humana
Parution : 2018-05-26
Collection : Cancer Drug Discovery and Development
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210,99
Télécharger le livre :  Hypoxia and Cancer
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???The imbalance between rapidly proliferating tumor cells and inadequate and inefficient tumor vasculature leads to a decrease in oxygen levels (hypoxia and/or anoxia) in tumor tissues. Intra-tumor hypoxia profoundly affects the biological behavior of cancer cells,...

Editeur : Humana
Parution : 2013-11-09
Collection : Cancer Drug Discovery and Development
ePub

147,69
Télécharger le livre :  Nuclear Signaling Pathways and Targeting Transcription in Cancer
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At the moment, there is no dedicated book to summarize the roles, the significance, and potential therapeutic targeting of transcriptional factors from the perspective of signaling cascade, and thus, directly impacting the functionality of transcriptional factors in...

Editeur : Humana
Parution : 2013-08-23
Collection : Cancer Drug Discovery and Development
ePub

147,69
Télécharger le livre :  Non-Hodgkin Lymphoma
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This book will be the first that focuses on solely on model organisms for lymphoma. It's editors are internationally recognized in the field.

Editeur : Humana
Parution : 2013-02-01
Collection : Cancer Drug Discovery and Development
ePub

147,69
Télécharger le livre :  Advances in DNA Repair in Cancer Therapy
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?A comprehensive review of the recent developments in DNA repair research that have potential for translational applications. The book explains in detail the various biological mechanisms by which cancer cells can circumvent anticancer therapy and limits its usefulness...

Editeur : Humana
Parution : 2012-12-09
Collection : Cancer Drug Discovery and Development
ePub

210,99
Télécharger le livre :  Natural Killer T cells
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This book will cover primary roles of NKT cells in immunity to cancer, in both mouse tumor models and cancer patients. There are several chapters describing general aspects of NKT cells.

Editeur : Humana
Parution : 2011-09-22
Collection : Cancer Drug Discovery and Development
ePub

94,94
Télécharger le livre :  DNA Topoisomerases and Cancer
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DNA topoisomerases represent an essential family ofDNA processing enzymes and a large number of topoisomerase inhibitors are used clinically for the treatment of various human cancers. Novels drugs are in clinical development both against type I and type II...

Editeur : Humana
Parution : 2011-09-21
Collection : Cancer Drug Discovery and Development
ePub

210,99
Télécharger le livre :  Insulin-like Growth Factors and Cancer
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The book will detail the history, successes, and failures of targeted therapies for cancer, with a particular focus on IGF systems and cancer.

Editeur : Humana
Parution : 2011-09-18
Collection : Cancer Drug Discovery and Development
ePub

147,69
Télécharger le livre :  Principles of Anticancer Drug Development
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A practical guide to the design, conduction, analysis and reporting of clinical trials with anticancer drugs.

Editeur : Humana
Parution : 2010-12-29
Collection : Cancer Drug Discovery and Development
ePub

147,69
Télécharger le livre :  Bladder Tumors:
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Bladder cancer is a common cancer of the urinary tract. It is the fourth leading cause of cancer-related death among men and the seventh among women. Clinical management of bladder cancer is challenging because of the heterogeneity among bladder tumors with respect to...

Editeur : Humana
Parution : 2010-12-16
Collection : Cancer Drug Discovery and Development
ePub

210,99
Télécharger le livre :  Tumor Models in Cancer Research
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The past 6 years since the first edition of this book have seen great progress in the development of genetically engineered mouse (GEM) models of cancer. These models are finding an important role in furthering our understanding of the biology of malignant disease. A...

Editeur : Humana
Parution : 2010-12-01
Collection : Cancer Drug Discovery and Development
ePub

210,99
Télécharger le livre :  Macromolecular Anticancer Therapeutics
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In spite of the development of various anticancer drugs, the therapy of cancer has remained challenging for decades. The current therapy of cancer is overwhelmed because of the inability to deliver therapeutics to all regions of a tumor in effective therapeutic...

Editeur : Humana
Parution : 2010-03-20
Collection : Cancer Drug Discovery and Development
ePub

273,25
Télécharger le livre :  Checkpoint Controls and Targets in Cancer Therapy
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Much work over the last two decades has firmly established that loss of cell cycle checkpoint regulation, and resultant unabated cellular proliferation, is an inherent characteristic of cancer. This loss may occur through aberration in any single component involved in...

Editeur : Humana
Parution : 2010-03-12
Collection : Cancer Drug Discovery and Development
ePub

147,69
Télécharger le livre :  Chemokine Receptors in Cancer
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Chemokines are a superfamily of low molecular weight cytokines that were initially described based on their ability to induce the directed migration of leukocytes to sites of inflammation or injury. In humans, there are approximately 45 chemokines that bind to 19...

Editeur : Humana
Parution : 2009-06-12
Collection : Cancer Drug Discovery and Development
ePub

147,69
Télécharger le livre :  Stem Cells and Cancer
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Significance of Stem Cells to Tumor Development Cancer stem cells remain a controversial topic and the criteria that define cancer stem cells are continuing to evolve. A recent surge in stem cell research has ignited a field of discovery into many human diseases...

Editeur : Humana
Parution : 2009-04-20
Collection : Cancer Drug Discovery and Development
ePub

210,99
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