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This one-stop reference is the first to present the complete picture -- covering all relevant organisms, from single cells to mammals, as well as all major disease areas, including neurological disorders, cancer and infectious diseases. Addressing the needs of the...
Editeur :
Wiley-VCH
Parution :
2014-07-31
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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Drug design is a complex, challenging and innovative research area. Structure-based molecular design has transformed the drug discovery approach in modern medicine. Traditionally, focus has been placed on computational, structural or synthetic methods only in isolation....
Editeur :
Wiley-VCH
Parution :
2014-07-16
PDF, ePub
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Plants and plant-derived compounds and drugs are becoming more and more popular with increasing numbers of scientists researching plant analysis. The quality control of herbal drugs is also becoming essential to avoid severe health problems, and in the future many more...
Editeur :
Wiley
Parution :
2014-07-15
PDF, ePub
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The first professional reference on this highly relevant topic, for drug developers, pharmacologists and toxicologists. The authors provide more than a systematic overview of computational tools and knowledge bases for drug metabolism research and their underlying...
Editeur :
Wiley-VCH
Parution :
2014-06-26
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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This atlas contains more than 700 illustrations that the authors have collected over the years as well as references and information pertaining to recently developed drug classes, including biologics. It is a useful bench reference for practicing pathologists and may...
Editeur :
Humana
Parution :
2014-05-13
ePub
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Prescribing Scenarios at a Glance is an innovative resource which allows medical students and junior doctors to practise prescribing skills safely for themselves. Supporting those who wish to develop their prescribing knowledge and clinical reasoning, this book features...
Editeur :
Wiley-Blackwell
Parution :
2014-05-07
Collection :
At a Glance
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A single-source reference with a broad and holistic overview of nonclinical studies, this book offers critical training material and describes regulations of nonclinical testing through guidelines, models, case studies, practical examples, and worldwide perspectives....
Editeur :
Wiley
Parution :
2014-05-02
PDF, ePub
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Can academia save the pharmaceutical industry? The pharmaceutical industry is at a crossroads. The urgent need for novel therapies cannot stem the skyrocketing costs and plummeting productivity plaguing R&D, and many key products are facing patent expiration. Dr....
Editeur :
Wiley
Parution :
2014-03-28
Collection :
Wiley Series on Technologies for the Pharmaceutical Industry
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Written by the pioneers of Viagra, the first blockbuster PDE inhibitor drug. Beginning with a review of the first wave of phosphodiesterase (PDE) inhibitors, this book focuses on new and emerging PDE targets and their inhibitors. Drug development options for all major...
Editeur :
Wiley-VCH
Parution :
2014-03-03
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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This book helps readers integrate in silico, in vitro, and in vivo ADMET (absorption, distribution, metabolism, elimination and toxicity) and PK (pharmacokinetics) data with routine testing applications so that pharmaceutical scientists can diagnose ADMET problems and...
Editeur :
Wiley
Parution :
2014-02-28
PDF, ePub
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Drug abuse has been, and continues to be, a global societal issue with diverse sets of impacts. Drugs of Abuse: Pharmacology and Molecular Mechanisms introduces the basic principles of pharmacology and neuroscience of drug abuse. Understanding the chemistry of commonly...
Editeur :
Wiley-Blackwell
Parution :
2014-02-27
PDF, ePub
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Mycotoxin contamination of food occurs as a result of crop invasion by field fungi such as Fusarium spp., Alternaria spp., Aspergillus spp., and Penicillium spp., which start their growth while in storage (storage fungi). In the worst case, these fungi produce secondary...
Editeur :
Springer
Parution :
2014-01-24
ePub
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Practical Pharmacology for the Pharmaceutical Sciences is a lab survival guide for those studying Pharmacology, providing hands-on advice on developing pharmacology laboratory and data handling skills. Suitable for both undergraduates and postgraduates, it focuses on...
Editeur :
Wiley
Parution :
2013-12-19
PDF, ePub
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The inspiration provided by biologically active natural products to conceive of hybrids, congeners, analogs and unnatural variants is discussed by experts in the field in 16 highly informative chapters. Using well-documented studies over the past decade, this timely...
Editeur :
Wiley-VCH
Parution :
2013-12-18
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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In this volume, the authors provide an excellent overview of how far the plant viral vector field has come. The discipline is no longer exclusively in the domain of academics—there is a small, but growing number of small biotechnology companies that exploit plant...
Editeur :
Springer
Parution :
2013-12-06
Collection :
Current Topics in Microbiology and Immunology
ePub
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This first systematic treatment of the concept and practice of scaffold hopping shows the tricks of the trade and provides invaluable guidance for the reader's own projects. The first section serves as an introduction to the topic by describing the concept of...
Editeur :
Wiley-VCH
Parution :
2013-11-06
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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Recent advances in understanding of fundamental immunology have created new insights into the dynamic interactions between tumors and the immune system. This includes new understanding of T- and B-cell interaction, immune inhibitory mechanisms including the biology of T...
Editeur :
Springer
Parution :
2013-10-25
Collection :
Current Cancer Research
ePub
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Cost-effective strategies for designing novel drug delivery systems that target a broad range of disease conditions In vivo imaging has become an important tool for the development of new drug delivery systems, shedding new light on the pharmacokinetics,...
Editeur :
Wiley
Parution :
2013-10-14
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Systematically examining current methods and strategies, this ready reference covers a wide range of molecular structures, from organic-chemical drugs to peptides, Proteins and nucleic acids, in line with emerging new drug classes derived from biomacromolecules. A...
Editeur :
Wiley-VCH
Parution :
2013-10-10
PDF, ePub
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Written for drug developers rather than computer scientists, this monograph adopts a systematic approach to mining scientifi c data sources, covering all key steps in rational drug discovery, from compound screening to lead compound selection and personalized medicine....
Editeur :
Wiley-VCH
Parution :
2013-09-25
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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