| |
A comprehensive introduction to using modeling and simulation programs in drug discovery and development Biopharmaceutical modeling has become integral to the design and development of new drugs. Influencing key aspects of the development process, including drug...
Editeur :
Wiley
Parution :
2012-07-31
PDF, ePub
|
Pharmacovigilance Medical Writing covers the preparation of pharmacovigilance documents for all stages of the drug development process (i.e. from clinical development through to applications for marketing authorisations to the post-marketing stage). For each document,...
Editeur :
Wiley-Blackwell
Parution :
2012-06-22
PDF, ePub
|
Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical...
Editeur :
Wiley-VCH
Parution :
2012-06-18
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
|
Human interaction with the environment remains one of the most pervasive facets of modern society. In a world characterized by rapid population growth, unprecedented global trade and digital communications, energy security, natural resource scarcities, climatic changes...
Editeur :
Springer
Parution :
2012-06-08
Collection :
Emerging Topics in Ecotoxicology
ePub
|
Environmental Toxicology is the third volume of a three-volume set on molecular, clinical and environmental toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals of daily life. By providing intriguing...
Editeur :
Springer
Parution :
2012-06-07
Collection :
Experientia Supplementum
ePub
|
New and emerging directions in pharmaceutical research to better treat schizophrenia Although the dopamine hypothesis has been the cornerstone of schizophrenia therapeutics, it is clear that dopamine-based approaches do not treat all aspects of the disease. Moreover,...
Editeur :
Wiley
Parution :
2012-06-06
PDF, ePub
|
Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for development. The first part provides a basic understanding of the factors governing protein-ligand interactions, followed by a...
Editeur :
Wiley-VCH
Parution :
2012-06-04
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
|
The opportunities and challenges of using dendrimers to improve drug delivery Among pharmaceutical and biomedical researchers, the use of dendrimers in drug delivery systems has attracted increasing interest. In particular, researchers have noted that the volume of a...
Editeur :
Wiley
Parution :
2012-05-23
Collection :
Wiley Series in Drug Discovery and Development
PDF, ePub
|
Cost-effective manufacturing of biopharmaceutical products is rapidly gaining in importance, while healthcare systems across the globe are looking to contain costs and improve efficiency. To adapt to these changes, industries need to review and streamline their...
Editeur :
Wiley-VCH
Parution :
2012-05-14
PDF, ePub
|
This book is meant to provide a complete overview of the research of HPV and its connection to cervical cancer.
Editeur :
Springer
Parution :
2012-04-27
ePub
|
The Latest Applications For Cellmechanism Research in Drug Discovery Designed to connect research on cell mechanisms with the drug discovery process, Therapeutic Targets: Modulation, Inhibition, and Activation introduces readers to a range of new concepts and novel...
Editeur :
Wiley
Parution :
2012-04-20
PDF, ePub
|
Learn why some drug discovery and development efforts succeed . . . and others fail Written by international experts in drug discovery and development, this book sets forth carefully researched and analyzed case studies of both successful and failed drug discovery and...
Editeur :
Wiley
Parution :
2012-04-19
PDF, ePub
|
A comprehensive guide to optimizing the lifecycle management of pharmaceutical brands The mounting challenges posed by cost containment policies and the prevalence of generic alternatives make optimizing the lifecycle management (LCM) of brand drugs essential for...
Editeur :
Wiley
Parution :
2012-04-16
PDF, ePub
|
The how's and why's of successful drug repositioning Drug repositioning, also known as drug reprofiling or repurposing, has become an increasingly important part of the drug development process. This book examines the business, technical, scientific, and operational...
Editeur :
Wiley
Parution :
2012-04-11
PDF, ePub
|
Explains how to perform and analyze the results of the latest physicochemical methods With this book as their guide, readers have access to all the current information needed to thoroughly investigate and accurately determine a compound's pharmaceutical properties and...
Editeur :
Wiley
Parution :
2012-04-11
PDF, ePub
|
This resource provides thorough coverage of pharmacogenetics and its impact on pharmaceuticals, therapeutics, and clinical practice. It opens with the basics of pharmacogenetics, including drug disposition and pharmacodynamics. The following section moves into specific...
Editeur :
Wiley
Parution :
2012-04-02
PDF, ePub
|
Mercury (Hg) is a global pollutant that knows no environmental boundaries. Even the most stringent control of anthropogenic Hg sources will not eliminate exposure given its ubiquitous presence. Exposure to Hg occurs primarily via the food chain due to MeHg’s...
Editeur :
Springer
Parution :
2012-03-23
Collection :
Current Topics in Neurotoxicity
ePub
|
This book provides a comprehensive look at renal cell carcinoma, exploring its biology as well as current and future molecular targets for renal cancer carcinoma.
Editeur :
Springer
Parution :
2012-02-28
ePub
|
The obesity pandemic continues to increase on a world-wide basis with over 70% of the United States population being either overweight or obese. Hematologic malignancies have recently been identified among the obesity associated malignancies spanning the lifespan from...
Editeur :
Springer
Parution :
2012-02-25
ePub
|
The only book dedicated to physiologically-based pharmacokinetic modeling in pharmaceutical science Physiologically-based pharmacokinetic (PBPK) modeling has become increasingly widespread within the pharmaceutical industry over the last decade, but without one...
Editeur :
Wiley
Parution :
2012-02-17
PDF, ePub
|