|
A comprehensive look at current drug discovery and development methods—and the roadmap for the future Providing both understanding and guidance in characterizing potential drugs and their production and synthesis, Development of Therapeutic Agents Handbook gives...
Editeur :
Wiley
Parution :
2011-10-24
Collection :
Pharmaceutical Development Series
PDF, ePub
|
Filling a real knowledge gap, this handbook and ready reference is both modern and forward-looking in its emphasis on the "bench to bedside" translational approach to drug development. Clearly structured into three major parts, the book stakes out the boundaries of...
Editeur :
Wiley-VCH
Parution :
2011-10-24
PDF, ePub
|
Development of Vaccines: From Discovery to Clinical Testing outlines the critical steps, and analytical tools and techniques, needed to take a vaccine from discovery through a successful clinical trial. Contributions from leading experts in the critical areas of vaccine...
Editeur :
Wiley
Parution :
2011-10-11
PDF, ePub
|
This book will examine current issues and controversies in the design of clinical trials, including topics in adaptive and sequential designs, the design of correlative genomic studies, the design of studies in which missing data is anticipated. Each chapter will be...
Editeur :
Springer
Parution :
2011-10-09
Collection :
Applied Bioinformatics and Biostatistics in Cancer Research
ePub
|
This book, which is the translated version of a Swedish book, combines a general introduction of a variety of antibiotics with a more in-depth discussion of resistance. The focus on resistance in learning about antibiotics will help future scientists recognize the...
Editeur :
Wiley
Parution :
2011-10-07
PDF, ePub
|
The subject of Tumour-Associated Macrophages is of interest in the cancer research community, and this book promises to be among the first to discuss a definitive theory on the role of macrophage in tumor development.
Editeur :
Springer
Parution :
2011-10-06
ePub
|
In recent years, cancer stem cells have been recognized as important component in carcinogenesis and they seem to form the basis of many (if not all) tumor types. Cancer stem cells or "cancer cell like stem cells" have been isolated from various cancers of different...
Editeur :
Springer
Parution :
2011-10-06
ePub
|
F. Schweda and A. Kurtz: Regulation of Renin Release by Local and Systemic FactorsM. Krauss and V. Haucke: Shaping Membranes for EndocytosisB.M. Jockusch and P.L. Graumann: The Long Journey: Actin on the Road to Pro- and Eukaryotic CellsB. Colsoul, R. Vennekens and B....
Editeur :
Springer
Parution :
2011-09-28
ePub
|
The book that highlights mass spectrometry and its application in characterizing proteins and peptides in drug discovery An instrumental analytical method for quantifying the mass and characterization of various samples from small molecules to large proteins, mass...
Editeur :
Wiley
Parution :
2011-09-26
PDF, ePub
|
This is the second edition of a book called "Lymphoma of the Nervous System," which was published by Butterworth-Heinemann (B-H) in 2004. Lymphoma and Leukemia of the Nervous System is a comprehensive review of this challenging group of diseases and should be useful for...
Editeur :
Springer
Parution :
2011-09-24
ePub
|
The first book to focus on comprehensive systems biology as applied to drug discovery and development Drawing on real-life examples, Systems Biology in Drug Discovery and Development presents practical applications of systems biology to the multiple phases of drug...
Editeur :
Wiley
Parution :
2011-09-23
Collection :
Wiley Series on Technologies for the Pharmaceutical Industry
PDF, ePub
|
This book will cover primary roles of NKT cells in immunity to cancer, in both mouse tumor models and cancer patients. There are several chapters describing general aspects of NKT cells.
Editeur :
Humana
Parution :
2011-09-22
Collection :
Cancer Drug Discovery and Development
ePub
|
DNA topoisomerases represent an essential family ofDNA processing enzymes and a large number of topoisomerase inhibitors are used clinically for the treatment of various human cancers. Novels drugs are in clinical development both against type I and type II...
Editeur :
Humana
Parution :
2011-09-21
Collection :
Cancer Drug Discovery and Development
ePub
|
A comprehensive resource on case studies of marketed kinase drugs and promising drug trials Since the discovery of protein kinase activity in 1954, the field of protein kinase drug discovery has advanced dramatically. With the ongoing clinical success of the Bcr-Abl...
Editeur :
Wiley
Parution :
2011-09-20
Collection :
Wiley Series in Drug Discovery and Development
PDF, ePub
|
The book will detail the history, successes, and failures of targeted therapies for cancer, with a particular focus on IGF systems and cancer.
Editeur :
Humana
Parution :
2011-09-18
Collection :
Cancer Drug Discovery and Development
ePub
|
This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate...
Editeur :
Wiley
Parution :
2011-09-09
Collection :
Wiley Series in Drug Discovery and Development
PDF, ePub
|
We are celebrating this year the hundred years´ anniversary of allergen-specific immunotherapy. In 1911 Leonard Noon published his seminal work “Prophylactic inoculation against hay fever” describing his attempts to achieve active immunity against “grass pollen toxin”...
Editeur :
Springer
Parution :
2011-08-26
Collection :
Current Topics in Microbiology and Immunology
ePub
|
Pharmacovigilance is the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other drug-related problems. This introductory guide is designed to aid the rapid understanding of the key principles of...
Editeur :
Wiley-Blackwell
Parution :
2011-08-24
ePub
|
The World Health Organization has identified chronic alcohol consumption as one of the top ten risk factors for worldwide burden of disease.The International Agency for Research on Cancer has identified alcohol as carcinogenic to humans, including cancers of the upper...
Editeur :
Springer
Parution :
2011-08-23
ePub
|
This book reviews the epidemiological associations between insulin resistance and cancer. This is followed by reviews of animal models which support this relationship and provide insight into potential mechanisms. Several chapters then provide detailed examination of...
Editeur :
Springer
Parution :
2011-08-19
Collection :
Energy Balance and Cancer
PDF, ePub
|